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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: DewDiligence_on_SI who wrote (16899)5/23/2005 10:41:46 AM
From: Biomaven  Read Replies (1) | Respond to of 52153
 
On Vivitrex you say:

In short, Vivitrex seems to work, but a monthly saline injection may work almost as well.

The fact is that Vivitrex showed a statistically significant effect: Compared with placebo, 380 mg of long-acting naltrexone resulted in a 25% decrease in the event rate of heavy drinking days (P = .02)

For men (who form the bulk of the relevant population), the effect was quite a bit stronger (hazard ration .56, with p value < .001).

I grant you the Barrons article (and the ALKS PR) are misleading in citing the drop without mentioning the drop in placebo as well, but the fact is the drug clearly works (much to my surprise). The fact is that right now there is no acceptable medical treatment - to argue that because the co-therapy provided most of the benefit that therefore the drug has no merit is incorrect in my view.

Peter



To: DewDiligence_on_SI who wrote (16899)5/26/2005 8:11:30 PM
From: rkrw  Read Replies (1) | Respond to of 52153
 
Dew, just one comment in response to the i-hub alks post you steered to. alks didn't "give away the store" to jnj on consta. Consta deal was inherited when alks bought out a small drug delivery company called medisorb. alks paid just $4M. Turned out to be a tremendous acquisition for alks earned many times over. Hesitance on vivitrex is certainly understandable, it's wait and see on that product.