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To: Skywatcher who wrote (24453)6/17/2005 1:13:13 PM
From: Bucky Katt  Read Replies (2) | Respond to of 48463
 
Bio/nano news>

Nanoparticles transport cancer-killing drug into tumor cells to increase efficacy, lower drug toxicity in mice

U-M scientists use folic acid as bait to get methotrexate inside tumor cells

ANN ARBOR, MI - University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells – increasing the drug's cancer-killing activity and reducing its toxic side effects.

Previous studies in cell cultures have suggested that attaching anticancer drugs to nanoparticles for targeted delivery to tumor cells could increase the therapeutic response. Now, U-M scientists have shown that this nanotechnology-based treatment is effective in living animals.
med.umich.edu