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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?

To: Ian@SI who wrote (17391)7/26/2005 2:59:55 PM
From: Biomaven  Respond to of 52153
 
Log 1.6 reduction is a 40-fold reduction I believe. So 100 units goes to 2.5. (Subject to correction by our math folks of course).

Extremely good numbers for monotherapy.

Peter



To: Ian@SI who wrote (17391)7/26/2005 3:01:45 PM
From: former_pgs  Read Replies (1) | Respond to of 52153
 
If it's log base 10, then you can take the value and use it as 10 exp (your value)

so: 10^1.6 = 39.8

10^1.84 = 69.18

So there was between a 39.8 and 69.18 fold decrease in viral load. For perspective, if the hypothetical initial value was 100, then a 39.8 fold decrease would take it to a final value of 2.51, and a 69.18 fold decrease would take it to 1.45.



To: Ian@SI who wrote (17391)7/27/2005 2:40:53 PM
From: Casaubon  Read Replies (1) | Respond to of 52153
 
1 log equals ten fold reduction
2 log equals one hundred fold reduction
3 log equals 1000 fold reduction
etc

10 to the power of the log number will give you the exact number (as someone else pointed out). More log units reduction means better response to drug.

90% reduction is 1 log unit
99% reduction is 2 log units

So, your presumption was correct.


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