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Biotech / Medical : Marshall Edwards -- MSHL -- Ignore unavailable to you. Want to Upgrade?

To: John McCarthy who wrote (15)	11/17/2005 3:23:54 PM
From: tuck	Read Replies (1) \| Respond to of 26

The market seems to be taking these results with a grain of salt. The cervical cancer press release is rather promotional in that stable disease is not response. Stable disease can mean the tumor grew or shrunk some. These being early results, we can hope that a later look will include some 50% plus tumor shrinkage. Also, I see the researchers looked at the resected cervical tumors for markers and evidence that postulated PK and MOA were being borne out in vivo. Not the tumors from the vulvas or vaginas? It would be nice to know which women had which cancers, i.e. a breakout of numbers of the women with cancer of the cervix, vulva, and vagina. And since when does 5/6=.928? Cheers, Tuck

To: John McCarthy who wrote (15)	11/17/2005 9:25:58 PM
From: tuck	Read Replies (1) \| Respond to of 26

One last note. As far as I can tell, "early stage" in this case means Stage II, which involves the vagina. meds.com From what I can divine, it's hard to say that one would expect obvious progression from time of diagnosis, as there are many variables -- not given in the PR or abstract -- that could affect the aggressiveness. So I'm not sure I buy Kelly's statement that we should expect obvious progression in a 4 week timeframe without treatment. I'd love to see a reference; I can't seem to track one down that addresses this point. All I can find is that women diagnosed with early stage cervical cancer have a 90% survival rate. I presume this is with treatment, either by surgery or chemo/radiation. Cheers, Tuck