To: richardred who wrote (1000 ) 1/28/2006 1:06:56 AM From: richardred Read Replies (1) | Respond to of 7243 If there were ever a more obvious talked about TOT this past six months. St. Jude gets the medal. I've heard Serono mentioned. Currently IMO that makes more sense. Why, a leader in birth control together with a world leader in infertility treatment. You never know! Also an old collaboration >The agreement with Serono represents Rigel’s fifth collaboration in oncology. Rigel has signed oncology partnerships with Merck on various ubiquitin ligase targets (signed 2004), Daiichi on a specific ubiquitin ligase target (2002), Novartis on anti-angiogenesis targets (2000) and Johnson & Johnson on cell cycle inhibition (1998). In addition, this is Rigel’s third major collaboration in the last 12 months.serono.com J&J May Eye St. Jude Medical for Takeover Friday January 27, 4:56 pm ET By Chris Williams, Associated Press Writer Johnson & Johnson's Next Takeover Target May Be St. Jude, Leader in Implantable Heart Technology MINNEAPOLIS (AP) -- Johnson & Johnson's next takeover target could be 30-year-old St. Jude Medical Inc., a quiet leader in implantable heart technology with a foothold in the promising business of implantable neurological devices. The company has about 20 percent of the market for implantable heart defibrillators, which regulate hearts that beat too fast or chaotically. That's a multibillion market expected to grow nearly 20 percent annually for the next several years. "These lend themselves to an ideal demographic of an aging worldwide population," said Steve Brozak, an analyst for WBB Securities LLC. Speculation that J&J would target St. Jude intensified last week when it lost out to Boston Scientific in the battle to acquire Guidant Corp. St. Jude -- the name has its roots with the founder's son -- got its start in 1976 making heart valves. It has maintained a focus on the valves and expanded into implantable cardioverter defibrillators -- or ICDs -- heart catheters, pacemakers and other devices to treat cardiovascular diseases. It's grown organically and through small acquisitions. Last year, it expanded its range with the $1.3 billion acquisition of Plano, Texas-based Advanced Neuromodulation Systems Inc., which makes implantables to treat chronic pain and other neurological diseases. With 2005 sales up 27 percent to $2.9 billion and defibrillator sales up 72 percent to $1 billion, St. Jude makes an attractive target for any big company seeking to buy predictable growth. It has been the subject of takeover rumors for years, but analysts say the company has no pressing need to sell. "They are not for sale, they are not looking to be for sale and they are happy doing what they are doing -- which is adding new products and growing like a weed," said Thomas Gunderson, an analyst with Piper Jaffray & Co. of Minneapolis. A St. Jude spokeswoman declined to make company executives available for interviews in time for this article. Earlier this week, she said the company has a policy of not commenting on mergers and acquisitions. Gunderson is among many Wall Street fans of the company. He said St. Jude has been picking up market share in defibrillators, has a "cash machine" in its mechanical heart valves and could see its new neuromodulation business grow 18 percent a year. "It has becoming increasingly clear that STJ is not 'just about ICDs' anymore," Gunderson wrote in a recent research report. The new products "demonstrate management's dedication to a broad-based growth strategy." The stock has risen steadily during the past 52 weeks. It rose 6 cents to close at $49.66 Friday on the New York Stock exchange, near the high end of its range of $34.48 to $54.75. The company has a low profile in Minnesota's medical technology sector, which includes Fridley-based Medtronic Inc. and Guidant Corp.'s cardiac rhythm management division in Arden Hills -- the other two major players in the implantable defibrillator market. Don Gerhardt, president of Medical Alley/MNBIO, a Minnesota trade group, said of St. Jude, "Their personality is of a quieter sort. They have just gone about their business in a very efficient way." The company was named in 1976 after St. Jude, the patron saint of lost causes, by founder Manuel Villafana as a way of saying thanks. Friends and family had prayed to the saint after his son, Jude, was born with a life-threatening condition. Young Jude recovered after corrective surgery at the University of Minnesota and the Mayo Clinic in Rochester, Minn. Both Brozak and Gunderson praised the company's management, led by Chairman and CEO Dan Starks. Gunderson said the company's prowess was evident as it picked up market share in defibrillators while Guidant stumbled through a series of recalls and safety advisories through much of 2005. "Another company could have been in that situation and not have been able to take advantage of the situation," Gunderson said. "They were ready to have good luck." St. Jude Medical: sjm.com biz.yahoo.com