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Biotech / Medical : Cell Therapeutics (CTIC) -- Ignore unavailable to you. Want to Upgrade?

To: Biomaven who wrote (801)	2/16/2006 3:55:21 AM
From: Icebrg	Read Replies (1) \| Respond to of 946

Peter, The only data available on Xyotax vs. control, that I have seen was presented by Dr. Socinski at last year's Chemotherapy Foundation Symposium. The aggregated results for woman from Stellar 3 and 4 as per Dr Socinski's presentation were: n Median Survival <55 years Xyotax 28 10,0 Control 22 5,2 > 55 years Xyotax 69 8,9 Control 79 8,6 Cancerconsultants made the following summary of what was presented at the conference: * Median overall survival among women with high estradiol levels was 300 days for those on the Xyotax arm, compared with only 167 days for those on the Paraplatin/Taxol arm (p=0.039) in the STELLAR 3 trial. * Median overall survival among all women in a combined analysis of the STELLAR 3 and STELLAR 4 trials indicates an improvement in survival of approximately two months in women treated with Xyotax compared to either chemotherapy regimen (9.4 months versus 7.7 months, respectively, p=0.03); however, it appears that this remains significant only in women under the age of 55 years * Women under the age of 55 years had a significantly improved survival on the Xyotax arms compared to the chemotherapy arms (10.0 months versus 5.2 months, p=0.038) * Survival at one year among all women in a combined analysis of the STELLAR 3 and 4 trials was 40% for women treated with Xyotax, compared with 25% for women treated with chemotherapy * There was no difference in survival between Xyotax or chemotherapy in men included in these trials * Xyotax was associated with a significant reduction in toxicities compared to either chemotherapy regimen professional.cancerconsultants.com