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To: PuddleGlum who wrote (17796)5/2/2006 1:06:50 PM
From: Galirayo  Read Replies (1) | Respond to of 23958
 
[GNBT] I noticed ALY this AM when they reported Earnings. Nice Move.

I'd Mention GNBT but if I do .. Ken will just want to short it again. Maybe I can Spook him enuff with this. >>Young Adult Type-1 Diabetes Mellitus<<

stockcharts.com

Message 22407038

Clinician Presents Generex Oral-lyn(TM) Clinical Data at the Pediatric Academic Societies' 2006 Annual Meeting
Tuesday May 2, 8:00 am ET
biz.yahoo.com

TORONTO--(MARKET WIRE)--May 2, 2006 -- Generex Biotechnology Corporation (NasdaqSC:GNBT - News), a leader in the area of buccal drug delivery, announced today that Dr. Jaime Guevara-Aguirre, M.D., of the Institute of Endocrinology IEMYR in Quito, Ecuador, was invited to make a late-breaker platform presentation of Generex Oral-lyn(TM) clinical data on May 1, 2006 at the Pediatric Academic Societies' 2006 Annual Meeting in San Francisco.
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Dr. Guevara's presentation was entitled "Preliminary Results from a 6-Month Study on the Safety and Efficacy of an Oral Insulin (Generex Oral-lyn(TM)) Administered at Lunch Time in Adolescent and Young Adult Type-1 Diabetes Mellitus Subjects Maintained on Basal Subcutaneous Glargine Insulin and Pre-Breakfast and Pre-Dinner Subcutaneous Regular Insulin."

"We are most gratified that the scientific community has recognized the importance of this study and the significance of these preliminary results and invited the principal investigator to make a podium presentation of the clinical data at this important scientific symposium," said Anna Gluskin, President & Chief Executive Officer of Generex.

Participating subjects in this 6-month study are 24 adolescents (12M; 12F) and five young adults (2M; 3F) referred to the Institute of Endocrinology IEMYR in various degrees of metabolic control as reflected by altered baseline measurements of glucose 236.6 (116.6) mg/dL; fructosamine 472.6 (126.6) umol/L; and glycosylated hemoglobin (HbA1c) 9.8 (2.3) g/dL. Baseline demographics of the 24 adolescents are: Age 14.7y (2.1); Bone age 14.1 (2.2); CA/BA 1.0 (0.1); Height 153.8cm (9.4); Weight 51.0kg (10.2); BMI 21.7 (3.2); Duration of DM 6.7 (2.8). Baseline demographics of the 5 young adults are: Age 20.6y (2.2); Bone age (BA) 18.8 (0.4); CA/BA 1.1 (0.1); Height 161.1cm (12.8); Weight 62.5kg (9.3); BMI 23.0 (1.8); Duration of DM 7.0 (1.7). Mean age for the entire group is 15.7y (3.0); BA 14.9 (2.7); CA/BA 1.1 (0.1); Duration of the DM is 6.8 (2.6).

After stabilization with basal subcutaneous glargine insulin and three pre-prandial subcutaneous regular insulin injections, standard therapy continued for four weeks for comparison. Immediately thereafter, split doses of Generex Oral-lyn immediately before and after lunch replaced lunch time injections of regular insulin. Patient-collected glucose values, fructosamine, and HbA1c were compared weekly (3-4 weeks per each treatment). Values are reported at the end of each phase.

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