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Biotech / Medical : Clinical Data Inc. -- Ignore unavailable to you. Want to Upgrade?


To: Mike McFarland who wrote (16)5/28/2006 4:15:06 AM
From: Mike McFarland  Read Replies (1) | Respond to of 39
 
"response marker"
clda.com

Surely this doesn't have to do with CYP3A4*1b variant--that
has to do with metabolizing drugs--not something so specific
has predicting a response to Vilazodone.


Patent Portfolio Expanded- Genaissance received a notice of
allowance from the U.S. Patent and Trademark Office. The
allowed patent, which is co-owned with Duke University,
claims testing for a common genetic variant in the CYP3A4 gene
to predict whether or not an individual is a poor metabolizer
of certain drugs. It is estimated at least 50 percent of all
drugs, including chemotherapeutic agents and a wide variety
of over-the-counter medications, are metabolized by CYP3A4.
Individuals with a reduced ability to metabolize these drugs
may be at risk for adverse drug reactions.