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Biotech / Medical : Theravance - THRX -- Ignore unavailable to you. Want to Upgrade?


To: Biomaven who wrote (37)8/27/2006 10:50:51 PM
From: DewDiligence_on_SI  Read Replies (1) | Respond to of 74
 
That wouldn't make any sense to me - that's not a two-bites at the cherry situation.

Strictly speaking this is two bites at the apple because a trial could hit either non-inferiority or superiority without hitting the other. In practice, hitting on superiority while missing on non-inferiority is rare, but it can happen.

A protocol where the aggregate 0.05 of p-value in split in half for each endpoint is fairly common.