To: scaram(o)uche who wrote (5552 ) 12/21/2006 3:56:28 PM From: freelyhovering Read Replies (1) | Respond to of 12215 What can you say about this product and the science behind it--Juvenon? QUESTION: I've heard there are two forms of alpha lipoic acid, one synthetic "S" and the other "R" natural. The body cannot metabolize the synthetic one and some people seem to be suggesting it is even harmful! I was also told that most alpha lipoic acid contains both S and R in roughly 50/50 proportions. Is any of this correct and what about Juvenon? michael ANSWER: The Juvenon supplement contains a racemic mixture of lipoic acid, including both the R and S isomers. Both are active as antioxidants, but only the R+ form is found in our bodies...we make it. Furthermore, the R+ form is the isomer that is utilized by the enzymes of the mitochondria for the conversion of food metabolites to energy. The S form cannot substitute for the R+ in these reactions. Juvenon will probably offer a product with the R+ form in the future, but only after we are certain it is, in fact, superior to the racemic mixture. Virtually all of the human studies to date (going back some 35 years) have utilized the racemic mixture with great results and a good safety record. No study to date has actually proven that either the R+ form or the racemic mixture is more effective for human health. In fact, there is some evidence to indicate the R isomer, once isolated from the S isomer, is very unstable and forms polymerized products that are clearly not natural. This problem, we feel, must be worked out before we are comfortable with switching to the pure R form. Send your questions to AskBen@juvenon.com. For more questions and answers, go to www.juvenon.com/product/qa.htm. Benjamin V. Treadwell, Ph.D., is a former Harvard Medical School associate professor and member of Juvenon's Scientific Advisory Board. the science | product | buy now | in the news | about us | contact © 2006 Juvenon, Inc Unsubscribe | Update Profile | Confirm | Forward