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Biotech / Medical : Targacept (TRGT) -- Ignore unavailable to you. Want to Upgrade?

To: tuck who wrote (19)	1/26/2007 4:40:14 PM
From: keokalani'nui	Read Replies (1) \| Respond to of 40

Here are my, uh, thoughts a couple weeks old. If they answer your question, great! 1/08/07 TRGT Price: $9.00 MC: $180m c/s: 19.1m (7/06) Cash: $68m est at 12/06. (Includes azn $20m milestone) Burn: $24m in 2006 IPO: $9/sh on 4/18/06, post-IPO value was $172m. Summary of value ($130m) 1. TC-1734 (a/k/a AZD3480), for AD and cognitive enhancement in schizophrenia. It has been in P2 and looks safe. AZN elected 12/06 to take it forward. Stepped low double digit royalty. $80m. 2. TC-2696. P2 in acute post-operative pain commenced 12-06. Doesn’t sound promising to me. $0m. The randomized, double-blind, single-dose trial is being conducted in the United States and is expected to enroll approximately 150 molar extraction patients. The trial includes five arms, 10, 25 and 50mg TC-2696, ibuprofen (400mg) as a positive control and placebo. 3. TC-2216, a product candidate for depression and anxiety disorders and other indications, such as obesity. P1 began 1/8/07. $40m. 4 TC-5619, a preclinical product candidate selective for NNR alpha7, b/u to x1734, with potential for schizophrenia, cognitive impairment and inflammation should be in P1 1H07. $10m. Add $30m when in the clinic. 5. TC-5214. Not sure whether the top-line p2 results using mecamylamine hydrochloride are sufficiently robust to now take this, one of the enantiomers of mecamylamine hydrochloride, forward. $0m.