To: bentway who wrote (331786 ) 4/4/2007 5:07:00 PM From: longnshort Respond to of 1573023 Maybe this is your problem. Too much tofu induces ‘brain aging,’ study shows A Hawaii research team says high consumption of the soy product by a group of men lowered mental abilities By Helen Altonn Star-Bulletin Tapa Tofu is touted for its health benefits, but also may pose health risks, says a Hawaii scientist. A Hawaii study shows a significant statistical relationship between two or more servings of tofu a week and "accelerated brain aging" and even an association with Alzheimer's disease, says Dr. Lon White. The Pacific Health Research Institute researcher urged caution at a recent conference in Washington as scientists from around the world discussed the role of soy products in the prevention and treatment of disease. The symposium was sponsored by giant soybean growing and processing firms such as Archer Daniels Midland and DuPont. The largely unregulated food supplements industry is preparing to step up sales, claiming that isoflavones, plant chemicals found in high concentrations in soybeans, offer "natural" cures for breast cancer, osteoporosis, prostate cancer, heart disease, menopausal "hot flashes" and other chronic conditions. Negative conclusions But, White said in an interview, "The majority of scientists said the data they were talking about for beneficial effects on health is very weak" and doesn't really support health claims for soy foods. White and his associates have been studying diseases and aging in a group of Japanese-American men who volunteered for medical research in 1965. The Honolulu Heart Program began with 8,006 men born from 1900 through 1919. They were identified through World War II Selective Service registration records. In comparing the dietary habits and health of the Japanese-American men in the study group between 1965 and 1993, White said the scientists found "a significant link between tofu consumption during midlife and loss of mental ability and even loss of brain weight." The men were questioned about 27 foods and drinks, with data showing that those who ate more tofu were apt to have impaired mental ability, White said. Tofu was the only consistent link among the men, he said. The rate of brain impairment, which normally increases with age, also went up faster in the men who ate the most tofu, he said. "The test results were about equivalent to what they would have been if they were five years older," he said. "Guys who ate none, their test scores were as though they were five years younger." The brains of 300 men who died also were examined in a unique autopsy study conducted as part of the Honolulu aging project, White said. The 300 men didn't appear to have had any more strokes than the average person, and their blood vessels didn't look different. "But what I did see was (that) the simple weight of the brain was lower," he said. Shrinkage occurs naturally with age, but atrophy progressed more rapidly in those men who had consumed more tofu, White said. He said the wives of about 500 men also provided information about what they ate, and the findings correlated with what their husbands said.