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Biotech / Medical : Alexion Pharmaceuticals, Inc. (ALXN) -- Ignore unavailable to you. Want to Upgrade?


To: kenhott who wrote (782)4/24/2007 5:19:21 PM
From: Pseudo Biologist  Read Replies (1) | Respond to of 824
 
Speaking of legumes, here is another data point on CD200:

ajp.amjpathol.org

In particular, The CD200-CD200R pathway plays a critical role in attenuating EAE and reducing inflammation-mediated damage in the CNS. Strategies that up-regulate the expression of CD200 in the CNS or molecules that ligate the CD200R may be relevant as neuroprotective strategies in multiple sclerosis.

The ALXN mAb blocks CD200/CD200R, which leads to enhancement of immune response, so this is the flip side of the story.

PB



To: kenhott who wrote (782)4/27/2007 9:37:14 PM
From: scaram(o)uche  Read Replies (2) | Respond to of 824
 
Be glad to. Haven't read it yet. Skimmed quickly. Engineered human lines, transplanted into a sophisticated mouse model.

Highly irrelevant, fascinating model that can teach a ton.

So, I don't have a good memory, given exposure to agonists. People should remind me, when I don't get back to them. I barely remembered this one, and I very much appreciate being asked to summarize it.

Not nearly as rude as I appear to be. Remind me, please.

Back to the track meet. Great 110m race this afternoon. Son lost to arch rival by 0.06 seconds, closest yet.



To: kenhott who wrote (782)6/28/2007 2:55:55 PM
From: scaram(o)uche  Read Replies (1) | Respond to of 824
 
Ha! Found it!

Stuffed it in my CPR monograph..... will enjoy reading it this weekend, if not before. Back soon.