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Biotech / Medical : ADVENTRX Pharmaceuticals Inc (Anx) -- Ignore unavailable to you. Want to Upgrade?


To: Ruffian who wrote (92)5/21/2007 2:04:44 PM
From: Keith FeralRead Replies (1) | Respond to of 418
 
He's definitely one of the better analysts covering Adventrx. He sees the writing on the wall. Kind of like Gilder back in the Qualcomm days. Folate wins, do we want low concentration leucovorin requiring 2 hour infusional delivery or high concentration Cofactor requiring 2 minute bolus injection. Truly, the biggest drawback to 500 mL leucovorin is that it only supplies a POTENTIAL supply of folate via multistage metabolic breakdown. 60 mL Cofactor delivers direct form of folate in minutes, requiring no metabolic conversion.

Amazingly, it attracts more 5FU to the tumors to the cancer cells to shut down cancer cell replication, but Cofactor also recovers dna, rna, red and white blood cells in healthy cells since the intracellular concentration of folate is so high in the healthy cells. Higher response rate with elimination of anemia seems to be exactly what the FDA is looking for in first line cancer treatment.



To: Ruffian who wrote (92)5/22/2007 12:35:32 PM
From: Keith FeralRespond to of 418
 
I'm waiting to get a copy of Dawson James real comments yesterday about Cofactor and anemia.