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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: Clarksterh who wrote (23768)5/23/2007 11:16:52 AM
From: Biomaven  Read Replies (1) | Respond to of 52153
 
Was it something in the Press Release vs the article itself?

It's in the article itself (Table IV).

I see your point about the exclusion when you explain this from a purely cook-book statistical perspective, but from an intuitive perspective, if we have large trials with no events in either arm, then surely that says something about the both the absolute and relative (to placebo) risk from the drug.

From a purely statistical perspective, the methodology doesn't know, for example, that a "no event" trial wasn't conducted in a population of 15-year-olds with essentially no cardiac risk, in which case excluding the trial is entirely appropriate, or whether the population was relatively homogeneous with the other trials, in which case excluding the information from the no-event trial biases the analysis.

Statistics is a lot harder than it looks!

Peter