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Biotech / Medical : CRIS, Curis (formerly CBMI) -- Ignore unavailable to you. Want to Upgrade?


To: Mike McFarland who wrote (618)8/4/2007 1:18:04 PM
From: Mike McFarland  Read Replies (1) | Respond to of 668
 
Hedgehog--Genentech has a 50-patient phase I systemically
administered Hedgehog antagonist in 'locally advanced or
metastatic solid tumors that have relapsed after first and
second line therapy or for whom no clinically beneficial
therapy exists'

Wyeth is funding five Curis researchers for hedgehog for
neurologic disorders.

Wnt signaling pathway, discovery phase, is with Genentech
and no research funding for Curis.

In house, CUDC-101 is designed to inhibit EGFR, Her2, and
"Target A" which should be revealed in the fall.
"formal toxicology testing will be initiated early in the
fourth quarter of 2007"

June 30, 2007 cash, cash equivalents, marketable securities
and investments totaled $30,228,000 and there were 49,533,950
shares of common stock outstanding.