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Biotech / Medical : Biotech & Pharma.T.A, -- Ignore unavailable to you. Want to Upgrade?

To: Jibacoa who wrote (1865)	10/2/2007 11:36:26 AM
From: Jibacoa	Respond to of 3722

Re: KOSN I don't know what caused KOSN to tank on June 20-25 ( its volume on June 22 was up to 4,505,200), I guess some institutions decided to sell.<g> In early June it had said that the PI of its KOS-1584/R1645, a drug under co-development with Roche,demonstrated promising antitumor activity in patients with solid tumors,including patients with non-small cell lung, ovarian, breast, prostate, head and neck and other cancers & toxicities were "low-grade and manageable". It also had presented data from a dose-escalating P1b of its Hsp90 inhibitor, tanespimycin (KOS-953) in combination with bortezomib (Velcade(R), which showed a high degree of antitumor activity and tolerability in patients with MM that had previously progressed following treatment with several other therapies.(In Sep it announced that it had reached an agreement with the FDA on the design of its PIII for its Hsp90 inhibitor) And in early August it said that the license deal it had signed with PFE in December for its motilin receptor agonist,could reap $250M from the deal, & PFE was going to start a PI for GERD. I don't know either what caused Friday's spike.<g> bigcharts.marketwatch.com But KOSN seems to be on its way to erase its August dip.(I am watching to see if it can close above its April 16 H of 6.58 & if it will be able to test its Jan 30 H at 7.35 <g>) bigcharts.marketwatch.com The stock has been up 8% today. bigcharts.marketwatch.com Bernard