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Biotech / Medical : MGI Pharma MOGN New patents, anti cancer -- Ignore unavailable to you. Want to Upgrade?


To: tuck who wrote (1775)8/28/2007 4:28:16 PM
From: tuck  Read Replies (1) | Respond to of 1826
 
[A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis]

Full-text freebie.

bloodjournal.hematologylibrary.org

Can't find anything on AKR-501 in pubmed, but the above may serve as an intro to the concept of c-Mpl agonism. Unclear to me if Nissan is still developing NIP-004. It is clearly well behind AKR-501, however, and I don't see anything else going after this target. There are other compounds against the disease in development, such as Ligand's TPO mimic partnered with GSK, also in P2.

Cheers, Tuck