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To: carranza2 who wrote (23585)	10/6/2007 11:26:08 AM
From: gg cox	Respond to of 217677

C2, don't need beer, as cognition and memory, long gone.<g> Message 23944335

To: carranza2 who wrote (23585)	10/6/2007 3:46:08 PM
From: Maurice Winn	Respond to of 217677

That bossy lady shows excessive control freak tendencies, wanting to torment rats, presumably because she hasn't got a drunk husband to berate. Her conclusions, as usual, were wrong. She imputed motive to the rats which her experiment couldn't conclude. She says the drunk rats avoided the electric shock, showing they were better at remembering than the sober ones. No. What the test shows is that she has got low intelligence. What the test more likely showed than her conclusion is that the drunk rats were happy as they were and they didn't need any more hassle just now thanks very much, so they stayed off the electric shock. The sober ones, being curious chaps, wondered whether that electric shock was still going to be going. They were conducting scientific research, trying to work out why there was an electric shock in one cage, but not the other. To do the research, of course they went into the electric shock cage to test it out. She should have given them volt meters so they didn't have to actually walk in to do the tests. The silly psychologist assumes that the rats are not like humans who do things "because it's there". Swarms of people climb Mount Everest, with a high probability of dying and certain lengthy discomfort and fear stimulation and they have to PAY to do it. As a child, we went to a fun parlour where one paid money to do various things, one of which was to see how much electric shock one could take. <One test involved novel object recognition, where rats were placed in a cage with two small objects inside multiple times over a two-day period. Then, one object was swapped for a new toy and rats were scored based on how quickly they explored the unfamiliar piece. In a second paradigm, rats were trained to expect a shock when they crossed from a white compartment to a black one inside a cage; a day after training, the rats were put back in the cage to see if they remembered that the black side was dangerous. Among the normal rats, the animals that consumed moderate amounts of alcohol fared better on both tests compared with the teetotalers. Rats on a heavy alcohol diet did not do well on object recognition (and, in fact, showed signs of neurotoxicity), but they performed better than their normal brethren on the emotional memory task. > Did she ask the rats or just make the decision for them? I bet her husband, if she has one, drinks a lot. Or maybe she does. Meanwhile, she was wasting more of my tax on her stupid study <Maggie Kalev, a research fellow in molecular medicine and pathology at the University of Auckland in New Zealand > She should get a real job. Maybe as a bar tender. Mathew During should spend his time studying ways to stop H5N1 and derivatives, not boozed rats. <Matthew During, a professor of molecular virology, immunology and medical genetics at The Ohio State University College of Medicine and a principal investigator of gene therapy at Auckland, initially set out to study the role of N-methyl-D-aspartic acid (NMDA) receptors in the neuronal processes of normal and diseased animals. (NMDA receptors are critical to memory, because they regulate the strength of synapses (spaces) between nerve cells through which the cells communicate.) But during their research, they discovered that memory was enhanced when one of its subunits, known as NR1, was strengthened in the hippocampus (a central brain region implicated in episodic memory). They then reviewed previous experiments, which had turned up a link between alcohol consumption and NR1 activity. > Mqurice