To: Pogeu Mahone who wrote (112924 ) 4/17/2008 5:21:35 PM From: Skeeter Bug Respond to of 132070 zeus, you are obviously unfamiliar with the research out of harvard medical school that yielded the following results: relative risk of heart attack healthy - 1 cholesterol over 200 - 2 smoking 1 pack per day - 4 tg/hdl > 7 - 16 so, if your tg/hdl was over 7 and you didn't smoke, you were 4 times more likely to have a heart attack than if you smoked 1 pack of cigarettes a day with a normal tg/hdl. 4 times is *very* significant. tg/hdl is already included in your blood panel work - so the marginal cost is $0. although you may have to do some math yourelf. the copenhagen male study yielded similar results. the studied two groups, one with a tg/hdl < 1.7 and one with a tg/hdl > 6. the low tg/hdl participants who smoked, didn't exercise, suffered from hypertension and had elevated levels of ldl cholesterol had a significantly LOWER risk of heart disease than those who lived better in the elevated tg/hdl group. i'm not saying that crp is a bad indicator. it is actually pretty decent. dr. sears points out one study that showed middle aged men with elevated crp were at a 300% greater risk of developing alzheimer's 25 years down the road. this makes sense since inflammation causes elevated crp and, eventually, plays a huge role in alzheimer's. so, no, crp isn't a bad test, but it isn't the be all, end all test, either. neither is tg/hdl. they all indicate good information. dr. sears argues that aa/epa is the best measure available because that ratio tells you the relative ratio of the essential fatty acids that drive inflammation in the first place. iow, inflammation is the result to the aa/epa cause. it is moving up stream to get a handle on the cause of inflammation rather than deal with the results of inflammation. i doubt you will be able to understand this as you seem fixated on the idea of defending crp, but i hope the light bulb turns on for someone else who may read this.