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Biotech / Medical : Rigel Pharmaceuticals, Inc. (RIGL) -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (366)6/3/2008 8:17:55 AM
From: scaram(o)uche  Read Replies (1) | Respond to of 566
 
Folicular...... several patients at stable disease, appear to be resolving long-term into formal responses..... 8 of 11 patients demo'd clinical benefit. PR requires at least 50% reduction in lymph node size, took several months for a PR to evolve to CR. Some of the PRs have been "rather durable".

Have seen patients who have remained on drug for nearly a year with no significant toxicities. Published toxicity results with revlimid indicate more problems with low blood counts than with 788. Subset of patients of subset that were not heavily pre-treated had a transient INCREASE in blood counts.

Seeking a global partner who can handle indications for both autoimmunity and oncology.