To: Knighty Tin who wrote (115154 ) 8/17/2008 12:09:48 PM From: Skeeter Bug Respond to of 132070 knighty, a couple points about aspirin: 1. it is an anti-inflammatory. 2. since it prevents a variety of chronic conditions, what does that say about the inflammatory nature of said chronic diseases? 3. almost as many people die from the prescribed dose of aspirin as do from aids in the usa. aspirin works on eicosanoids, however, it is like a dumb bomb and "blows up" the beneficial eicosanoids along with the ones causing the problems. it blows up the eicosanoids responsible for the body's protective lining for the stomach. just like cholesterol, one needs a balance of "good" and "bad" to optimize health. if you have no "bad" cholesterol, you die. it is all about balancing pro-inflammatory eicosanoids and anti inflammatory eicosanoids to optimize health, wellness and physical and mental performance. that's why a diet that balances out pro and anti inflammatory eicosanoids can reduce diabetic incidences 83% *without* the use of aspirin's anti inflammatory effects. it is also why my friend was able to use diet to eliminate her back pain and stop taking her ulcer medication and the nurse who recommended this diet to me over a decade ago was able to stop taking over 15 aspirin a day to deal with her rsi related pain. this is why popping aspirin is not a reasonable substitute for using diet to modulate eicosanoid balance in order to get all th ebenefits of aspirin (and lots of other good benefits) without any of the bad side effects. enderstanding eicosanoids...drsears.com "Certain drugs can inhibit the cyclo-oxygenase pathway of this eicosanoid formation. The most well known is aspirin which literally destroys a cyclo-oxygenase enzyme on a one-on-one basis. This is what is known as a suicide inhibitor. When you are suffering from a headache or arthritic pain, you are overproducing "bad" eicosanoids, but in particular "bad" prostaglandins. The aspirin temporally shuts down all prostaglandin formation (but not leukotriene formation), until the cell can make more of the cyclo-oxygenase enzyme to replace the ones destroyed by the aspirin. However, you can't be using these suicidal soldiers forever, as aspirin also shuts down the synthesis of "good" prostaglandins, especially those that protect the stomach from dissolving itself. When that happens, you get internal bleeding. This is why there are more than 10,000 deaths per year associated with the over-use of aspirin."