Silicon Investor (SI) -- The First Internet Community

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Politics : Formerly About Advanced Micro Devices -- Ignore unavailable to you. Want to Upgrade?

To: bentway who wrote (434431)	11/12/2008 1:17:56 AM
From: Gersh Avery	Read Replies (1) \| Respond to of 1571926

A few months ago there was a compound, known to be in marijuana and other herbs, that was identified as a cannabinoid. This cannabinoid has CB2 affinity. Both CBD and THCV have CB2 affinity and have been tested against diabetes. CBD against type 1 and THCV against type 2. THC has also been tested against various aspects diabetes. However THC has affinity for both CB1 and CB2 receptors. The affinity toward CB1 receptors is what produces the marijuana high. Basically CB1 is for CNS systems and CB2 is toward lymphatic systems. (it's more broad than that. this is a simplification) THC gets a person high. CBD and THCV do not. In fact they lower the impact of THC. Before I was arrested for growing, I was focused on using techniques that would cause a gain in CBD production in marijuana plants. In addition to growing conditions I made use of the small leaves that grow close to the buds. These small leaves are supposed to contain higher concentrations of CBD than the buds do. These I used to make brownies, cookies and hash. Generally I put myself to sleep every night by eating brownies. I was able to be off my glucophague and bp meds for a year before I got arrested. The benefit lasted while I was in jail (41 days). My sugar levels were recorded every day at first. Then once per week. Normal readings the whole time. My bp went crazy in jail. Highest recorded reading was 235/135. I got out of jail just in time for the Christmas season. Blood sugars 350-400 readings so I started the gluphophague again. As soon as I saw that they had identified b-carryophylene as a cannabinoid I started to try out different spice and herb oils that contain this cannabinoid. These oils and blends of oils I make produce a wonderful pain killing effect when applied to the skin directly over the pain. They turn off pain like a light switch. Not an entirely unexpected effect from a cannabinoid. They take effect in seconds and their effects could last for days. After working with these cannabinoid bearing spice oils for about a month I ran into a formulation called the "Holy oil of anointing." It's listed in the book of Exodus. It consists of two different kinds of cinnamon, myrrh and what bible translators have translated "calamus" in a olive oil base. The people promoting this oil claim that the hebrew word Kanahbos should have been translated cannabis instead of calamus. In this formulation I perceived a blend of cannabinoid bearing materials favoring the CB2 receptor. Yet with a THC balance. A broadband cannabinoid therapudic medicine. The formulation of which had been isolated by a possible few centuries of human trial and error experimentation. Or, if you choose to consider this possibility, directly from God himself. Either way would be good. Very good. This oil was used to keep people, places and things "clean." In the old testament being "unclean" many times involved having a disease. I haven't begun working with this bible formulation yet. But I've seen some pretty impressive results of it being used. Against open diabetic sores. One of which had been infected with gangrene. These cases had new skin growing over bone that had been exposed for years. I mention it because of the similarities to the oil blends I've been working on. Some people have taken my oil and added THC to it. The reports I've gotten back suggest that by including THC into the mix the pain killing effect is multiplied. Not enough THC to get high. But enough to get the THC into the area of pain. A topical oil that doesn't get you high. Yet takes advantage of our bodies cannabinoid system. It saturates through skin all the way into bone. It turns off pain while leaving all the other nerve receptors functional. And that's just where it starts. Some of the properties: anestetic anti inflammatory anti fungal anti viral anti biotic anti tumorial anti cancer That's the very short list of what has been mentioned in medical literature about cannabinoids. And herbs and spices that have this newly classified cannabinoid. I might continue this after 12/4 when the new law goes into effect. In the meanwhile I would be happy to send some of this oil out without the THC to anyone. Two methods can be used to add the THC content, if so desired. 1. Get a prescription from your doctor for marinol. Cut open the marinol caplet and add the oil to my oil. 2. Take the best bud you can get. Best to use a sweet smelling strain. Bake it for about a half hour at 300F. Let cool and then cover the baked bud with 99% iso alcohol. Let soak in the iso for about an hour then strain off. Reduce the iso to about one quarter of it's starting volume and then add it to my oil. In the best of worlds some company would do this extraction. It is a dangerous procedure. Many people have been burned very badly doing these kinds of extractions. Again, the oils that I've been working with work with or without THC. When THC is added to my oil, it increases the effect without producing a high. It is possible to get high from it, but that would require covering a large area of someones body. A one word answer to your question could have been "topically." I've been walking on a broken back for decades and have brusitus. That gives you some idea of the quantities of pain killing oil I've been applying. This is the second set of cannabinoids that I've seen drive back my diabetes. The first directly from marijuana before I was arrested. The second from these oils as a topical application after jail. I would expect that this kind of thing wouldn't work for everyone with diabetes. I do know it works for me. I've applied my oil to a couple of hundred people, so far, as a painkiller. I've seen it take out neuropathic pain and carple tunnel in seconds. I've seen it knock out the pain in someone with no cartilage left in their knees. I've seen these oils fail with some people when a single herb oil is used. The blends seem to have worked on 100% of people so far. For most, pain was gone in seconds. For the rest pain was reduced. I haven't yet identified a class of pain that it doesn't work on. So while using a topical cannabinoid application my body goes into this "shut down diabetes" mode again. Medical tests seem to show that these CB2 affinity cannabinoids are where most of the anti diabetes effects reside. There are other parts of the marijuana plant that are of great interest to me also. Compounds that are the smell and taste of the plant all vaporize easily. These compounds could be collected in the same way herbal essential oils are collected. That process would collect these volatile compounds without the THC and other cannabinoids. These may have even more medical value than the cannabinoids do. There is a blend of THC and CBD that is being evaluated by the FDA. It is a oral spray called Sativex. The company that produces Sativex is the company that is testing THCV in human studies against type 2 diabetes. This is the only company in the world that is producing medicine from extractions of marijuana. They grow their own. CB2 affinity cannabinoids reduce a certain blood compound by as much as 70%. This compound blocks insulin receptors and causes inflammation of the pancreas. When this compound is lowered in the blood, the pancreas begins to return toward normal function as the inflammation is reduced. Insulin sensitivity returns also. I don't know how much diabetes is reversed by these compounds. Don't know if I ever will. My body seems to have returned to very nearly normal function. BTW b-carryophylene has been approved by the FDA as a food additive. "Diet, Weight, BMI, Exercise regieme" none of them.

To: bentway who wrote (434431)	11/12/2008 10:37:49 AM
From: Gersh Avery	Respond to of 1571926

quote Suppression of insulin action in the liver resulting from TNF-alpha-mediated suppression of tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) is at least one of the mechanisms of insulin resistance in this model, the investigators report, and TNF-alpha blockade restored insulin sensitivity. end quote Nice to note the "restored insulin sensitivity." Here is where I got that quote from: icmag.com The medical study quoted from was about Hep-C causing type 2 diabetes. TNF-alpha plays a strong role in type 1 diabetes development. In another study, about type 1, the University of Jeruslam documented the 70% reduction of TNF-alpha in type 1 diabetic mice when CBD was applied. Onset of expected diabetes was delayed or stopped in something like 86% of the test subjects.