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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (33263)12/30/2009 2:33:41 PM
From: Pseudo Biologist1 Recommendation  Read Replies (1) | Respond to of 52153
 
Apparently the antibody has been around for 1/4 of a century now:

ncbi.nlm.nih.gov

Clin Immunol Immunopathol. 1984 Nov;33(2):268-81.

[One] hybridoma, designated F77-129, was extensively purified and used to characterize a PC-3 antigen.

One wonders what motivated them to look back at "the freezer" after all these years.

For a number of reasons (glycolipid target, antibody tested is a mouse IgG3, etc) "grain of salt" is right. The naked antibody works impressively as monotherapy in a couple of xenograft prostate cancer mouse models, so, yes, it is worth exploring.

Greene likes to claim some credit, I guess deserved to some degree, on the HER2 (Herceptin) story, FWIW.

ncbi.nlm.nih.gov (p185 is an older name for HER2)

PB



To: scaram(o)uche who wrote (33263)12/30/2009 5:05:16 PM
From: Arthur Radley  Read Replies (2) | Respond to of 52153
 
Are you saying that Greene falls in the category of our dear friend, Dr. Lindsey Rosenwald? Speaking of Rosenwald, haven't seen any of his 'deals' lately in the news, but I'm sure he is lurking around to bring forth another sure winner.

Are you going to leave the poke in the ribs about you over on the 2010 contest board.....with no response?????? (:>) As for who might be the guy in the blue shirt........didn't know you were such a hunk! Levi Johnson might have someone bumping him out of a job. (:>)