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Biotech / Medical : Indications - Neurodegenerative -- Ignore unavailable to you. Want to Upgrade?

To: DewDiligence_on_SI who wrote (348)	4/21/2010 1:08:32 AM
From: John McCarthy	Read Replies (1) \| Respond to of 448

I am in over my head "language wise" but got curious as to how many companies are in this IVIG thingie. Googled :IVIG products This spit out what I was after -- but suspect it is a short list as opposed to complete list ... Product ..................... Manufactured By Liquids: --------------- Flebogamma® ..................... Grifols Privigen ..................... Liquid CSL Behring Gamunex ..................... Talecris Biotherapeutics-USA Octagam® ..................... Octapharma Gammagard ..................... Liquid® Baxter Healthcare Powders: --------------- Carimune ..................... NF ZLB Behring Gammagard® S/D ..................... Baxter Healthcare Gammar® P ZLB ..................... Behring Iveegam EN ..................... Baxter Healthcare Panglobulin® NF .....................American Red Cross Polygam® S/D .....................American Red Cross Would you know a goto source link that identifies all makers (world-wide) And was curious if liquid vs powder makes a difference. nbninfusions.com Various other diseases and immune disorders where IVIG is used include: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Multiple Sclerosis (MS) Myasthenia Gravis(MG) Systenic Lupus Erythematosus (SLE) Guillain-Barre Syndrome (GBS) Autoimmune Diabetic Neuropathy Polymyositis Multifocal Motor Neuropathy (MMN) Dermatomyositis Rheumatoid Arthritis (RA) Common Variable Immunodeficiency (CVID) Hypogammaglobulinemia Severe Combined Immunodeficiency (SCID) Wiskott-Aldrich Syndrome (WAS) X-Linked Agammaglobulinemia (XLA) other connective tissue disorders EDIT wendyusuallywanders.wordpress.com From what I have read, each bottle of Ig contains plasma components from at least 3000 people. I believe I got 8 bottles worth. That means the immune system components of perhaps 240,000 to 800,000 people are now running around inside of me No wonder a war is raging! Each batch of IVIg is made by cold ethanol fractionation (the Cohn process) of human plasma derived from pools of 3000 to 10 000 donors. The product is purified by enzymatic treatment at a low pH, which is followed by fractionation and chromatography. The purified immunoglobulin is stabilized with glucose, maltose, glycine, sucrose, mannitol, or albumin. The final product contains more than 95% IgG, less than 2.5% IgA, and a negligible amount of IgM. Among the IgG subclasses, IgG1 varies from 55% to 70%, IgG2 from 30% to 38%, IgG3 from 0% to 6%, and IgG4 from 0.7% to 2.6%, according to the size and composition of the donor pools used in the various proprietary IVIg preparations. EDIT EDIT IVIG products March 2006 clinimmsoc.org