To: richardred who wrote (2305 ) 7/23/2010 7:15:49 PM From: richardred Read Replies (3) | Respond to of 7252 Sanofi May Be Looking, But Is Any Biotech Worth Buying? Lisa LaMotta JUL 02, 2010 12:50 PM Sanofi May Be Looking, But Is Any Biotech Worth Buying? The Big Pharma is rumored to be in the market for a big US biotech company, but most of the potential targets come with too much baggage. Rumors have been making waves since late Thursday night that Sanofi-Aventis (SNY) is in the market to make a biotech acquisition in the US of more than $20 billion. The news reportedly came from five people with knowledge of the situation, according to an article by Bloomberg, which said the company had called a special meeting to talk about the deal that's still in its infancy. The news agency didn’t identify its sources or expound on possibilities of what company might be the target. Sanofi-Aventis told Minyanville that it wouldn't comment on market speculation. While Chris Viehbacher, Sanofi’s chief executive, has made it clear to the public and investors that the French drugmaker does intend to make plenty of acquisitions, he's also said that they'd be on a small-to-mid-size scale. If the reports of a pending acquisition are true, it would be completely out of character for the Big Pharma. “A major acquisition would not be consistent with their recent past; it would be a total strategy shift,” said Miller Tabak analyst Les Funtleyder. Since Viehbacher has taken the reigns at Sanofi, the company has made more than 15 deals -- with only one garnering a price tag of more than $2 billion. That purchase was the company’s acquisition of Merck’s (MRK) half of its animal health and vaccine business Merial for a reported $4 billion. Viehbacher has even said publicly that he plans to stick to acquisitions of $15 billion or less. (A timeline of all of the recent Sanofi acquisitions can be seen at FierceBiotech.) These reports beg the question, why would Sanofi change its game plan? The answer to that question could easily be that it needs to build up its pipeline and pad its bottom line against the brunt of generic competition. Funtleyder considers Sanofi’s pipeline to be less than stellar, but certainly far from being in the worst shape amongst its Big Pharma brethren. He believes that companies like Merck, Bristol-Myers Squibb (BMY), and Novartis (NVS), would be on the better end of the spectrum, while Pfizer (PFE) and Eli Lilly (LLY) occupy the losing end. Beyond its pipeline, Sanofi needs to make up for revenues that it's losing to generic competition for some of its major drugs, including the blockbuster blood thinner Plavix and the cancer treatment Eloxatin. Analysts point to the fact that the French drugmaker has a lack of biotech capabilities and a less-geographically diversified R&D model as other reasons why this sort of acquisition might be underfoot. But what companies could the Big Pharma be interested in? Speculation is swirling around US-based biotechs like Genzyme (GENZ), Allergan (AGN), and Biogen Idec (BIIB), all of which trade above $40 per share and have a market cap above $12 billion. (All three companies have seen experienced gains in their share price since the rumors began.) Yet, all three of these companies come with plenty of problems. Both Genzyme and Biogen Idec have had nasty battles with activist billionaire investor Carl Icahn in their recent histories. Biogen hired a new CEO, George Scangos, earlier this week after fights with Icahn caused long-time Chief Executive James Mullen to leave the company. Critics have been questioning whether Scangos is a good choice, due to his lack of knowledge concerning all areas of Biogen’s business. He joined the company from a smaller drugmaker, Exelixis (EXEL). If Sanofi were to buy Genzyme, it would be inheriting a Consent Decree from the FDA. The biotech received the punishment and hefty fines for problems within its manufacturing facilities. The problems have caused two of its major drug candidates to have significant shipping delays and lose market share to competition. (For more on Genzyme’s woes, see Is Shire the Next Genzyme, Minus the Headaches?) As for Allergan, which many think would be the best fit for Sanofi, it has plenty of issues as well. The company is best known for its cosmetic product Botox. Allergan is currently caught up in a swath of litigation due to its marketing of off-label uses. The company has been preaching the merits of Botox as a therapeutic solution to migraines, despite not gaining approval from the FDA for this indication -- a major no-no. Allergan has since filed suit to seek permission to espouse the benefits of Botox beyond cosmetic purposes. Fears have surfaced that terrorists could use Botox’s active ingredient, the deadly botulism toxin, as a biological weapon. Allergan has denied that the blockbuster drug could pose a threat. Despite the positives for all of these companies, their baggage is pretty extensive, and no one likes to strike up a new relationship with someone who has a lot of baggage. “We don’t know where this speculation is coming from or what the agenda of those people could be,” added Funtleyder. “I don’t think this information could be coming from Sanofi because it's not in their interest to have this information out there.”minyanville.com