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Politics : Evolution -- Ignore unavailable to you. Want to Upgrade?


To: Jacques Chitte who wrote (12295)1/6/2011 7:04:10 PM
From: Solon  Read Replies (1) | Respond to of 69300
 
Yep, they call it "mercy killing" for a reason. Because it is assisting someone to die at their competent request out of a compassionate mercy.

I always thought the Bromptobn Cocktail would be the best. It was given in England for years--illegally while people looked the other way knowing their loved one died in peace.

"Brompton Cocktail also know as Bromptom Hospital Mixture is a formulation which used to enjoy widespread use before the war on drug intensified. The rational was that through a combination of diferent classess of drug, the dying patient would be able to achieve maximum relief with the greateset amount of reposiveness to his or her environment, hence the inclusion of a stimulant. The clasic Brompton's mixture contained morphine or diacetylmorphine (heroin), cocaine to counteract sedation/nonresposiveness, chlorpromazine to prevent nausea,hyoscinine, and ethyl alcohol. In time, the mixture was fine tuned. This was at first used to produce palliative care in TB patients and in terminal cancer, and other terminal other conditions. In the original formulation, cannabis extract was replaced by thorazine which is of a questionable rational. I would have stayed with the cannabis extract (THC helps manage opiate prcipitated asthma, among other things -one pharmacological property is that of a bronchiodialator.) Cannabis is an unsurpaced antiemetic/ increases apetite, but in its abscence, if the goal is to prevent nausea promethazine which is a phenothyazine (thorazine/chlorpromazine) derivative is an excellent derivative. Find this in codeine with phenergan preparations often.Has wide degree acceptance among dope fiends-use to hear for sale alot 6 years ago at my old methadone clinic @ BAART Civic Center by 6th and market. Other agents were tried at various times with greater or lesser effect. Most notably, amphetamines were substituted for cocaine increasingly over time and gained greater acceptance due to half-life and because clinical studies did not find any improvements in analgesia by cocaine whereas dexedrine, on the other hand decreases the amount of opiates to achieve equianalgesic doses and has the saltutory side effect of increasing the energy level, morale, mentation, lucidity, and decreasing opiate requitements (has possibly opiate sparing effect paradoxically). (This is cited in Goodman & Gilman's 9th edition.)

From my standpoint, in the practice of hopsice nursing and end of life care the dose would have to be individualized. But this is what i think a good place to start would be:

1.)Dilaudid x mg (whatever opiate works best for individual- immediate release
2.) Cocaine (2 grain maximum), more 1/2 grain (about 30 mg)
3.) 10-40 mg desoxyn
4.) "high worm-wood"Absinthe diluted with sugar and water to a final palatable concentration for one with a weak stomache. If not absinthe, a pleasant alcoholic based bezerage with a final proof of 10-40 (5-20% alcohol by volume). Also, a tincture of cannabis of a strain with extra emetic/ low anxiety paranoia properties shouls be added.
5.) Long acting narcotic formulations taken apart from Brompton's to maintain theapeutic plasma concentration.
6.)Methaqualone/Mandrax- In contrast to barbituates has been found to potentiate analgesia and acts as an antitussive by itself= barbituates can exacerbate pain especially in the presence of delerium.
7.) Xanax 0.25-2 mg compounded in depending on individual person's respose.
8. ) Possible low dose ketamine certain circumstances.
9.) Chloral Hydrate, Tuinal, placydyl to given sleep with.
10.) MDMA and other hallucinogens, entactogens offered in conjunction with counseling at some point when a terminal diagnosis seems certain.

The idea is to make the person's last weeks and months tolerable without side effects limiting full relief and optimum functioning. In my opinion, in the last hours or days this coctail could be administered IV with practical modifications."

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