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To: ForYourEyesOnly who wrote (225)11/22/1997 10:56:00 AM
From: John McCarthy  Respond to of 569
 
THC

(1) Well aware of Eduardo's thoughts. And I agree with them.

(2) ANIK helps my P&L.

BMY brings additional marketing $$$ and raises awareness
of the new solution to osteoarthritis.

Total AHP estimated penetration rate of only 1.9% for
1998. Plenty of room for ANIK.

(3) If there aren't any NEWS shows (the typical News show
that YOU watch) by February showing a 30 second spot
about this new WONDER DRUG then I am concerned about
SYNVISC and I THEN KNOW that AHP isn't a player.

Whats a player?

PFE:VIAGRA:COVER OF MAGAZINES ALREADY

SP:ALLEGIES:ATE HMR LUNCH

BMY:TOLD JAPAN GOVERNMENT TO HIT THE ROAD WITH RESPECT
TO TAXOL

Some up here have a strong good feeling about AHP.
I don't.

Why is good press important? Builds upward momentum.
And reduces 2.2% problem to a footnote where it belongs.

No press gives BMY an opportunity to exploit it.
And they will.

(4) I don't own ANIK. As you know I own tons of NPRO and am
getting killed. I think 9/10 a share is cheap.

I DO NOT think FDA approval is in the bag.

Especially if BMY files an injunction against NPRO/FDA
if FDA approves PAXENE.

People are people.

Regards,

John






To: ForYourEyesOnly who wrote (225)11/22/1997 1:07:00 PM
From: John McCarthy  Read Replies (1) | Respond to of 569
 
THC

Your question this morning has made me realize that there
is a lack of understanding of the osteoarthritis problem
to some degree, and consequently, a big mis-understanding
of how IMPORTANT Synvisc is.

If you want, please take the following test. I think it
will shock you. And you will think I'm full of it.

Background Info:

NSAID's:Non-steroidal anti-inflammatory drugs

Examples:
Ibuprofen (Motrin and Advil)
Indomethacin (Indocin)
Sulindac (Clinoril)
Naproxen (Naproxyn)

The Test:

Select from these Answers Only:

A - NSAID
B - There is no medical problem of this nature

Q1 - FDA #1 category of adverse drug events is gastrointestinal
complications and it is caused by ?????

Q2 - #1 cause of blood transfusions in hospitals is because
of ?????

Q3 - These drugs cause 25% of the people who take them to
develop ulcers. ??????

Q4 - 20,000 people a year die from gastrointestinal complications
that come about from taking these drugs. ??????

Q5 - If you take these drugs your body CANNOT heal joints or
regenerate cartilage. ??????

Q6 - These drugs tend to WORSEN the rate at which there occurs
degeneration of CARTILAGE. ?????

Please do not ask me to verify this stuff. I won't.
But you might want to check it out.

Why does the FDA allow NSAID's?

Pain hurts, and until SYNVISC there really are very few
options.

You see, it is a MULTIPLE cure. It not only fixes the problems
but it also cleans up the mess we currently have
with NSAID's.

And this is really the big picture.

Regards,

John