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Biotech / Medical : Zonagen (zona) - good buy? -- Ignore unavailable to you. Want to Upgrade?

To: Tunica Albuginea who wrote (867)	11/22/1997 12:02:00 PM
From: DR. BOND	Read Replies (3) \| Respond to of 7041

TA......The mere fact that Arsenio would publish such a negative, detailed SELL REC. on Zona should at least raise some caution flags amongst long time ZONERS, instead it raises a backlash of criticism at ARSENIO. After so many posts in the past about the possibility of Zona not being all that Mr. P states, and all the medical data about the "questionable effects" of oral Phentolamine" for treating ED you would think people such as Dauntless would at least "agree that the possibility exists here that Zona may never get approval of Vasomax"! Oh Well! Just my OPINION! DB PS. Why hasn't the ANALYST AT VOLPE Publicly Supported Zona during all this controversy? Mighty strange since Volpe is Zona's main Underwriter!

To: Tunica Albuginea who wrote (867)	11/22/1997 3:04:00 PM
From: Dauntless	Read Replies (1) \| Respond to of 7041

Thank you for the attempt at a logical & consistent response. You started out pretty well but, as usual, your uncontrollable urge to rant took over & you lapsed back to your normal style at the end. You seem to be particularly unable to maintain continuity between posts. To refresh your memory - your original message implied that phentolamine was VERY dangerous for its ability to drop a patient's blood pressure precipitously. Your example used IV administration - as opposed to oral - which, since missed the point, was what I challenged you on - now in this post you offer the following: ---------------------------------------------------------------- THERE WAS NO ORAL PHENTOLAMINE GIVEN AT THAT TIME FOR ANY REASON, GGGGG -THERE WAS NO ORAL PHENTOLAMINE GIVEN AT THAT TIME FOR ANY REASON, GGGGG -THERE WAS NO ORAL PHENTOLAMINE GIVEN AT THAT TIME FOR ANY REASON, GGGGG -THERE WAS NO ORAL PHENTOLAMINE GIVEN AT THAT TIME FOR ANY REASON, GGGGG BECAUSE BECAUSE BECAUSE - the half life is too short ( 5 min ). -that means you have to give a very large amount orally to have enough drug around to get any effect. -------------------------------------------------------------------- So which is it? Is it very dangerous because of its POWERFUL vasodilutive action? - Or is it very safe because "you have to give a very amount orally to have enough drug around to get any effect". Next, if you have no idea about the blood levels resulting form IV infusion, how can you so definitively warn against the dangers of an oral administration. I'll bet that Zonagen measured the blood levels very carefully. I don't know whether your an MD or not - I'd certainly never let you near me or any of those I care for - because your too emotional & too easily carried away by your own beliefs. Your reference to ASHOLIO as your brother will draw no criticism from me. Thread - maybe, in honor of the season, we should change this guy's nom de plume from TUNA to TURKEY??