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Biotech / Medical : Infinity Pharmaceuticals -- Ignore unavailable to you. Want to Upgrade?

To: tuck who wrote (189)	1/17/2016 2:51:47 PM
From: scaram(o)uche	Respond to of 210

Sorry, following your link from momotif, don't have this thread bookmarked and thus probably never saw your post. Thank you, nice link. >> FAAH inhibition leads to increase of various actors which play a role in inflammation, thus a paradoxical state is induced, one we would like to avoid. << Hmmmmmm...... well, I'll follow along if I can..... the intent of inhibiting FAAH is to augment the quantity of endogenous cannabinoids and to inhibit (at least peripheral) inflammation. I didn't know anything re. brain mediators and their upregulation. None of these patients have died suddenly??....... https://clinicaltrials.gov/ct2/results?term=JNJ-42165279&Search=Search Etc. Looks like an off-target issue, first blush.