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Biotech / Medical : Array Biopharma, Inc -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (202)11/9/2012 6:23:49 PM
From: mcbio1 Recommendation  Read Replies (2) | Respond to of 321
 
Very unhappy with the offering (namely the price) but holding for key data in 1H13 on 614 and 520. Posted notes on the NVS R&D Day at: siliconinvestor.com .



To: scaram(o)uche who wrote (202)10/21/2013 9:55:44 AM
From: scaram(o)uche  Read Replies (2) | Respond to of 321
 
>> Next, we might watch for a telegraphed combo, 162 and LEE011 (CDK4/6 inhibitor) <<

Ms. Church is out tweeting for ASH, and she says....

Sally Church ?@MaverickNY 15h
LEE011 + BYL719 leads to tumour regression in PIK3CA mut breast cancer models #targets13 @AdamsLisa

Sally Church ?@MaverickNY 15h
LEE011 will also be combined with MEK162 in NRAS mut melanomas and with LGX818 to prevent emergence of resistance #targets13 v interesting

Sally Church ?@MaverickNY 15h
Whoa, IC50 for NVS new CDK4/6 inhibitor LEE011 are very low! Read <0.05. Being evaluated in pediatric tumours #targets13