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To: 5,17,37,5,101,... who wrote (232)12/4/1997 10:32:00 PM
From: flickerful  Read Replies (3) | Respond to of 756
 
a now familiar theme revisited...( do you think artie consulted frosty
on the need for this release?)

Cytoclonal Pharmaceutics Confirms Paclitaxel (Taxol(R)(1)) Position

DALLAS, Dec. 4 /PRNewswire/ -- The following release was issued today by
Cytoclonal Pharmaceutics Inc., ("CPI" or the Company)
(Nasdaq: CYPH, CYPMW, CYPHZ):

In response to investor inquiries regarding company stock activity,
Arthur P. Bollon, Ph.D., chairman and chief executive officer, said today that
the recent decision by Immunex Corporation to challenge Bristol-Myers Squibb's
Paclitaxel (Taxol(R)(1)) position and patents does not adversely affect CPI
which is currently developing a fungal fermentation process to produce a
better supply of more cost-effective Paclitaxel. Microbial fermentation is
considered one of the most cost-effective methods to make drugs such as
antibiotics. On October 7, 1997, the company announced patent claim approval
for broad claims to any microorganisms isolated from the yew tree that make
Paclitaxel.
CPI also has exclusive worldwide rights for technology, developed at UCLA,
for Paclitaxel treatment of Polycystic Kidney Disease (PKD). Patent claims
for this potential new use of Paclitaxel were recently allowed, as announced
by the company on September 16, 1997. This potential new use of Paclitaxel is
outside the domain of other Paclitaxel patents presently held by other
companies, and is also outside the domain of the recent action taken by
Immunex.
More than 5 million people worldwide, including 500,000 in the US, have
PKD. Of those in the US, 300,000 to 400,000 people could be candidates for
the potential treatment using Paclitaxel. Presently, approximately 200,000
cancer patients are under Paclitaxel (Taxol) treatment, resulting in a market
projected to exceed $1 billion this year. New indications for the drug, such
as the potential treatment of PKD, could have a significant impact on the
total Paclitaxel market.
CPI also is developing a diagnostic test and therapeutic products for lung
cancer based on a human gene, LCG, isolated by CPI scientists and patented in
December 1996. The lung cancer gene and protein product and a melanoma-
related protein are being developed to target cancer drugs such as Paclitaxel
to reduce toxicity. The company, which is also isolating other human cancer
genes, is scheduled to present its research at an invited lecture at the
Cambridge Healthcare Conference on the Human Genome Project in San Francisco
from February 9-11, 1998.

Cytoclonal Pharmaceutics Inc. is a biopharmaceutical company developing
therapeutic and diagnostic products for various diseases such as cancer and
infectious diseases.

(1) Marketed by Bristol-Myers Squibb

SOURCE Cytoclonal Pharmaceutics Inc.

CONTACT: Arthur P. Bollon, Ph.D., Chief Executive Officer of
Cytoclonal Pharmaceutics, 214-353-2921; or Thomas Redington of
Redington, Inc., 203-222-7399, or 212-926-1733

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