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Biotech / Medical : Cell Therapeutics (CTIC) -- Ignore unavailable to you. Want to Upgrade?

To: Regis McConnell who wrote (5)	1/26/1998 11:57:00 AM
From: Jeffers Hughes	Respond to of 946

Wake up, CTIC holders. CTIC has finished its first phase III trial. [ Business \| US Market \| Industry \| IPO \| S&P \| International \| PRNews \| BizWire \| Finance Home ] Friday January 23, 5:06 pm Eastern Time Company Press Release Cell Therapeutics Completes First Phase III Trial of Lisofylline SEATTLE--(BW HealthWire)--Jan. 23, 1998--Cell Therapeutics Inc. (cti) (Nasdaq: CTIC - news) today announced that the last patient completed treatment and the subsequent 100-day evaluation period in its first pivotal Phase III trial of lisofylline. The trial was a multi-center, randomized, double-blind, placebo-controlled trial designed to assess the effect of lisofylline in patients with advanced hematological malignancies undergoing high dose radiation and/or chemotherapy accompanied by bone marrow transplantation (BMT) from related (sibling) donors. Enrollment in the trial totaled 132 patients. ''This trial is one of the largest studies in BMT recipients, and we are anxious to see if the results are comparable to those of the similarly designed Phase II trial we previously reported. Since one of our primary endpoints is survival at 100 days post BMT, we needed to wait for the last patient to reach that evaluation point before finishing data clean up and validation,'' said James A. Bianco, MD, president and CEO. ''We are on target to release preliminary results of this first pivotal lisofylline trial by the end of the first quarter of 1998 as planned.'' Lisofylline is being developed to prevent or reduce the incidence of serious and fatal infections, mucositis and treatment-related mortality among cancer patients receiving radiation and/or chemotherapy. The Company also has an ongoing pivotal Phase III trial among patients undergoing induction chemotherapy to treat acute myeloid leukemia. A third pivotal Phase III trial is ongoing for patients receiving ablative radiation and/or chemotherapy followed by BMT from unrelated donors. Both patient groups are at high risk for serious and fatal infections. cti anticipates completing enrollment in these two trials later this year. This news release includes forward-looking statements that involve a number of risks and uncertainties, the outcome of which could materially adversely affect actual future results. Specifically, the risks and uncertainties that could affect the development of lisofylline and related compounds includes risks associated with preclinical and clinical development in the biotechnology industry in general and of lisofylline and related compounds in particular (including, without limitation, the potential failure of lisofylline and related compounds to prove safe or effective for treatment of disease), determinations by regulatory, patent, and administrative governmental authorities, competitive factors, technological developments, costs of developing, producing, and selling lisofylline and related compounds, and the risk factors listed or described from time to time in the Company's filings with the Securities and Exchange Commission including, without limitation, the Company's Registration Statement on Form S-1, and the Company's most recent reports on Forms 10-K, 8-K and 10-Q. Cell Therapeutics Inc. focuses on the discovery, development and commercialization of small molecule drugs that selectively regulate the metabolism of oxidized lipids and phospholipids relevant to the treatment of cancer and inflammatory and immune diseases. Contact: Cell Therapeutics Inc. Lee M. Parker, 800/664-CTIC invest@ctiseattle.com www.cticseattle.com businesswire.com More Quotes and News: Cell Therapeutics Inc (Nasdaq:CTIC - news) Related News Categories: biotech, medical/pharmaceutical Help Copyright c 1998 Business Wire. All rights reserved. All the news releases provided by Business Wire are copyrighted. Any forms of copying other than an individual user's personal reference without express written permission is prohibited. Further distribution of these materials is strictly forbidden, including but not limited to, posting, emailing, faxing, archiving ina public database, redistributing via a computer network or in a printed form. See our Important Disclaimers and Legal Information. Questions or Comments?