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Politics : Mainstream Politics and Economics -- Ignore unavailable to you. Want to Upgrade?

To: koan who wrote (51491)	8/23/2013 2:22:26 PM
From: Brumar89	1 Recommendation Recommended By FJB Respond to of 85487

Cannabis abuse in adolescence and the risk of psychosis: A brief review of the preclinical evidence. Speaking of science. Rubino T, Parolaro D. SourceDepartment of Theoretical and Applied Sciences, Biomedical Research Division, University of Insubria, via Manara 7, 21052 Busto Arsizio VA, Italy. Abstract Epidemiological studies suggest that Cannabis use during adolescence confers an increased risk for developing psychotic symptoms later in life.However, despite their interest, the epidemiological data are not conclusive, due to their heterogeneity; thus modeling the adolescent phase in animals is useful for investigating the impact of Cannabis use on deviations of adolescent brain development that might confer a vulnerability to later psychotic disorders. Although scant, preclinical data seem to support the presence of impaired social behaviors, cognitive and sensorimotor gating deficits as well as psychotic-like signs in adult rodents after adolescent cannabinoid exposure, clearly suggesting that this exposure may trigger a complex behavioral phenotype closely resembling a schizophrenia-like disorder. Similar treatments performed at adulthood were not able to produce such phenotype, thus pointing to a vulnerability of the adolescent brain towards cannabinoid exposure. The neurobiological substrate of the adolescent vulnerability is still largely unknown and experimental studies need to elucidate the cellular and molecular mechanism underlying these effects. However, the few data available seem to suggest that heavy adolescent exposure to cannabinoids is able to modify neuronal connectivity in specific brain areas long after the end of the treatment. This is likely due to disruption of maturational events within the endocannabinoid system during adolescence that in turn impact on the correct neuronal refinement peculiar of the adolescent brain, thus leading to altered adult brain functionality and behavior. ncbi.nlm.nih.gov Science. Can you accept that use in adolescence is dangerous?

To: koan who wrote (51491)	8/24/2013 9:47:35 AM
From: TimF	Read Replies (1) \| Respond to of 85487

You cannot ask that question without invoking social science Sure you can. In fact nothing in social science can determine it, at best it can inform the decision, it can give you facts that you use to feed in to your decision making process, but the actual process is based on philosophy, ideology, morality, and politics, not science. We have monopolies, and fixing of markets. You should be aware of all these tings, I shouldn't to explain them to you. I am aware of such things, that's why I call for smaller government, since its government doing all of these things. They are not so much the cause of inequality (although they may contribute to it), as they are caused by inequality, but not in this case income or wealth inequality as much as inequality of political power. If political power was not used as much, if the government was smaller and less active then this harm wouldn't happen. Its not inequality that's the source of the harm, but rather a big interfering government directed by politicians to support their cronies and supporters or whoever has the most political pull. In days past laws allowed slavery, chain gangs and union busting. And in the past the earth didn't exist, while in the future the expansion of the sun will heat things up enough to make Earth no longer able to support life. All sorts of negative conditions have existed and will exist, but none of this is very relevant. It doesn't address the question.