The probable lethal dose of nicotine has been reported as between 40 and 60 milligrams (the total amount in about 2 cigarettes if all of the nicotine was absorbed) in adults and about 1 mg/kg in children (less than 1 cigarette) .[7][8][9] Children may become ill following ingestion of one cigarette,[10] ingestion of more than this may cause a child to become severely ill.[11][5] In some cases children have become poisoned by topical medicinal creams which contain nicotine.[12] People who harvest or cultivate tobacco may experience Green Tobacco Sickness (GTS), a type of nicotine poisoning caused by dermal exposure to wet tobacco leaves. This occurs most commonly in young, inexperienced tobacco harvesters who do not use tobacco.[4][13]