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Biotech / Medical : ARRIS - Another partner -- Ignore unavailable to you. Want to Upgrade?


To: Miljenko Zuanic who wrote (316)12/12/1997 2:04:00 AM
From: John Dwyer  Read Replies (2) | Respond to of 353
 
>>I hope you will agree that target validation in drug development is
as important as identification of the drug which will selectively
interact with target. Because of the complexity of diseases pathology
genomic discovery (target selection) can improve probability that drug
will have effects in diseases control. Today strength of the genomic
bt companies speak for itself.<<

Yes, I agree. I also agree that the valuations of many genomics
companies reflects the value of this approach. My question is why
did ARRS feel the need to _buy_ a company? Why not just partner? There
is also a fair degree of overlap in the programs between the two
companies (osteoporosis, etc). It would have made perfect sense to
partner with SQNA to find targets. By buying SQNA, they only save the
10% (or less) royalty, right? They still have the development costs
and they will still, in all likelyhood, have to partner again later
to fund development into Phase III. It really doesn't make sense to
me. I still bet they were looking for something in particular.
Something in SQNA's pipeline looked good enough to buy outright... I
haven't had time to really look for what it might be.

I think it will be difficult for ARRS in the near-term. These types
of buyouts are usually difficult to digest (at least for companies
outside biotech). Until I have a clearer picture of what the long
term plan involves, I can't really say how this will affect them
several years out.

John



To: Miljenko Zuanic who wrote (316)12/12/1997 2:19:00 AM
From: John Dwyer  Read Replies (1) | Respond to of 353
 
Off topic...

Miljenko,
Chris is a post-doc in Bart deVos' lab who came to
Genentech about the same time I did. He's a good crystallographer
and that was not an easy structure to solve. However, it was not
the basis for the anti-VEGF work... this was done mainly in the
lab of Napoleone Ferarra.

With respect to VEGF/KDR, we are obviously interested in that
complex but I can't really comment on that at this point. Sorry.

John