To: bentway who wrote (254901 ) 7/3/2014 3:43:13 PM From: Wharf Rat Respond to of 541701 I worked the summer of '67 for a guy who did a lot of research in Cerro de Pasco. This is one of the papers which came out of that summer.jap.physiology.org We were also doing similar studies on us, both in SF and at Barcroft. One of the Peru studiesjap.physiology.org John was busy..Dr. Severinghaus is Professor Emeritus of Anesthesia at the University of California in San Francisco. He was a Senior Staff Member of the Cardiovascular Research Institute. He was born in Madison, Wisconsin on May 6, 1922. After majoring in physics he designed radar test equipment at MIT during World War II During medical school he developed the first electrophrenic respirators. He published the first measurements of the rate of uptake of N2O during anesthesia. From 1953-1958, he was chief of anesthesia research at NIH, especially studying the use of hypothermia in surgery. He introduced the CO2 electrode and the first blood gas analysis system. In 1958, he joined UCSF in the Cardiovascular Research Institute and a new anesthesia department. In 1964 on sabbatical in Copenhagen, Severinghaus designed a blood gas slide rule relating oxygen pressure to hemoglobin saturation, and solving acid base and altitude problems. With help of many colleagues he published the standard human oxygen dissociation curve, with a simple equation, and accurate corrections for temperature and pH effects. Severinghaus held an NIH Research Career Award from 1963 to 1991. His 350+ publications concern physiology of respiration and pulmonary and cerebral circulation, location of the medullary ventral surface CO2 chemoreceptors, physiologic effects of anesthetics, of high and low Pco2 and Po2, of high altitude on natives and newcomers on the lung, on cerebral blood flow, brain acid base balance and respiratory control. He developed and tested instruments such as pulse oximeters, brain and transcutaneous blood gas electrodes, introduced multiplexed mass spectrometry for multi-patient monitoring in surgery and through this, pioneered the introduction of computers in clinical anesthesia. smartvoter.org