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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: aknahow who wrote (5134)12/17/1997 8:22:00 PM
From: Maxer  Respond to of 17367
 
Somehow, we gotta crank up the publicity machine. Let the world know about XOMA. Granted, this is a tough time with the market so uncertian, but start now, the market will be receptive by the time the material is ready.

Somehow, XOMA has to say: we got this, and this, and this is in phaise III, etc. I'm totally of the belief you aren't discovered unless you make yourself discoverable. Web sites and publicity releases are cheep, fast, and can be effective. Use 'em.



To: aknahow who wrote (5134)12/17/1997 8:57:00 PM
From: Robert K.  Respond to of 17367
 
George good investigative work. Thanks. BTW IMO new patents arnt "that" important. BPI patents excite me though. Max, they will toot their horn when its really worth tooting. Also I thought T&A stood for something more important ;-) -well to me anyways.



To: aknahow who wrote (5134)12/18/1997 8:45:00 AM
From: Robert K.  Read Replies (2) | Respond to of 17367
 
At least 2 presentations. Some heavy hitters there. This presentation and wording peaks my interest even more......

.2:45 Antifungal Peptides Derived from Bactericidal/Permeability-Increasing Protein: Preclinical Research Summary

Roger G. Little, PhD, Director, Biochemistry Department, XOMA Corporation

While elucidating BPI's structure and function, we have discovered that peptides from a particular region (amino acids 142-169) within BPI had unexpectedly potent activity against Candida albicans. Utilizing an iterative synthesis/screening process, the initial activity has been amplified into a series of peptides characterized by:

fungicidal activity against a broad range of fungal genera in vivo antifungal activity in mortality and target organ CFU analysis fungicidal activity against polyene- and azole-resistant Candida albicans

Currently, lead compounds have been prioritized based on in vivo efficacy in murine systemic candidiasis and aspergillosis models and on in vitro fungicidal activity.

(nothing we dont know but..............)