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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?

To: William who wrote (3859)	12/18/1997 1:41:00 AM
From: Zebra 365	Read Replies (2) \| Respond to of 23519

Here is the actual press release about the Letter, (not a peer reviewed study) written to the Lancet by Dr. Greco. Read this press release and then go to the VVUS web site and look at the real studies there. The full-text letter was not available at the Lancet web site. thelancet.com but this press release came from the Lancet web site. This is not how people of science go about determining the truth..... FURTHER TESTING OF DRUG FOR IMPOTENCE (p 1682) Doctors from Italy report in a Research Letter in The Lancet that a drug called alprostadil can improve penile function. 123 men underwent tests with this drug and improvement in blood flow into erectile arteries of the penis was shown in all patients and an increase in penis volume in almost all patients. The drug was inserted into the urethra, and its passage into the penile arteries followed. Dr Ermanno Greco and Dr Paolo Polonio-Balbi from Rome, Italy, measured the rigidity of the penis by a penile buckling test rather than the "Erection Assessment Scale" that has been used to evaluate this drug in the past. The buckling test was positive when a weight of 1 kg (2.2 pounds) did not buckle the organ, and was judged complete when pressure within the penis was 75 mm Hg after visual erotic stimulation. Of the 123 men investigated, 11 had complete penile rigidity and 16 a full, but not lasting, erection. The increase in penis volume found was not related to hardness. Hope this was a soundproof office, great way to clear a waiting room Contact: Dr Ermanno Greco, Centre for Impotence and Fertility, Rome, Italy; tel +39 6 884 2213. Zebra P.S. I spoke with Dr. Greco a week ago and faxed him these questions, I have not received a reply: Dear Dr. Greco I would very much appreciate your reply, either by Fax at ******* or by E-Mail at ******** 1. I would appreciate an abstract of your study from which the Letter in the Lancet was published on alprostadil suppository, if available. 2. Do you have a CV or list of prior publications? 3. If you do not have an abstract, perhaps an outline of the methodology? i.e. - How and where were weights attached? - Was buckling measured at the base or mid-shaft? - Was a certain degree of angulation defined as buckling? - Were there any control subjects? - Have you done similar tests with injectable alprostadil? 4. Are you involved in testing any other drugs for ED; Oral, Injectable, or cream? 5. Was this study funded by government, private, or pharmaceutical company? Thank you for your kind attention ********, M.D.