To: Machaon who wrote (12811 ) 12/24/1997 8:43:00 AM From: Henry Niman Respond to of 32384
Biotechs are weak in Europe also. The large number of failures in advanced clinical trials has affected the sector in the US as well as the UK: Biotechnology: Further gloom for sector TUESDAY DECEMBER 23 1997 By Daniel Green The shares of Biocompatibles and Scotia fell sharply yesterday, underlining the difficulties of the UK biotechnology sector. Scotia shares fell 52«p to 265p in response to the announcement after the market closed on Friday that health regulators had blocked the launch of Tarabetic, a drug to treat diabetes. The shares touched 735p at their 1997 peak in January. Biocompatibles lost another 20p to 457«p as the company issued a statement saying sales would not reach planned targets, and that a partnership with a mainstream pharmaceuticals company was still some way off. Biocompatibles' shares peaked in April at œ14.18. The gloom spread across almost the entire sector, even affecting companies which have enjoyed a relatively good year, such as Cortecs and Chiroscience. There has been a series of failures in clinical trials this year, the most important of which was Celltech's drug to treat septic shock, abandoned in May. The biotechnology sector has a history of volatility. Although some companies, such as Scotia, have sales, stock market valuations are based more on the perceived prospects of drugs in research. Scotia's Tarabetic was aimed at patients suffering from the nerve damage caused by diabetes. The Medicines Control Agency, which oversees the sale of medicines in the UK, first blocked its approval in March. At the time, David Horrobin, Scotia chief executive, said he and some diabetes experts felt the evidence from clinical trials was strong enough to warrant approval. On Friday, the MCA disagreed and confirmed the block. This month Dr Horrobin announced he was leaving the company he founded in 1979. The Horrobin family intends to sell its 17 per cent stake in Scotia over the next few years. Biocompatibles' share price has been weak since the company announced in September that its talks to form a partnership with Johnson & Johnson, the US health care products company, had been largely abandoned. Biocompatibles makes a plastic coating friendly to the human body. The coating is used to cover stents (wire mesh implants to hold open blood vessels), catheters and contact lenses. J&J is one of the world's big stent suppliers. Alistair Taylor, chief executive, said yesterday that Biocompatibles was holding talks with several other companies which might lead to the formation of two partnerships to develop and distribute its stents, one for heart products and one for other products. The contact lens side was having mixed fortunes too, held back by "slower than expected" sales in the US.