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To: JT who wrote (15040)	12/24/1997 10:49:00 PM
From: JPR	Read Replies (1) \| Respond to of 27012

Hello JT: OTOT <<I have heard theories that different ethnic groups have different level of aldehyde dehydrogenase and therfore clear acetaldeyde at diffent rates>> Thank you for your post. True, Some Japanese have inactive aldehyde dehydrogenase-2 (ALDH2) and therefore have problem with accuumulating acetaldehyde in the body, which causes all the symptoms similar to pretreatment with Antabuse in alcoholics. Antabuse, as you well know, blocks the enzyme aldehyde dehydrogenase. Therefore people with inactive ALDH2 are genetically programmed and protected against alcoholism, eventhough some exceptions are known. Happy holidays Paul