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Biotech / Medical : Apricus Biosciences -- Ignore unavailable to you. Want to Upgrade?


To: eico20 who wrote (1628)1/13/2016 11:54:46 AM
From: eico20  Read Replies (1) | Respond to of 2026
 
OK MI, so predicting clinical outcome of Fis. is critical, I think it will be positive, but you never know in these trials, TRT doesn't always show benefit in sexual function, I do like the show of confidence in this recent slide on evidence for Fis in sexual function:

Prior studies conducted in hard to treat men (PDE failures) with erectile dysfunction show improvements in IIEF-EF at 300mg Fispemifene daily in conjunction with sildenafil
?Some sub-populations (men with diabetes) showed greater benefit

Current Study:
?Dose at 450mg
?Broader patient population (including above populations)
?Lead-in designed to minimize placebo response/exclude placebo responders
?Additional supportive diaries (Sexual Encounter Profiles)