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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?


To: BigKNY3 who wrote (4032)12/25/1997 12:53:00 PM
From: MisterED  Read Replies (3) | Respond to of 23519
 
I am tired of reading all the same rehashing of doctors and
scientists opinions. They all disagree with each other and
they are probabely all indirectly involved with with the
company or product they defend and promote. I only trust
the FDA review board. Muse is approved, Viagra is not.
And remember, Viagra takes an hour to work and lasts 5-10
minutes. Muse works after 5 -10 minutes and last for an
hour or more. Nobody disputes that. Happy New Year.



To: BigKNY3 who wrote (4032)12/30/1997 3:49:00 PM
From: Tunica Albuginea  Read Replies (2) | Respond to of 23519
 
BigKNY3, Re: " Mr Ed: Here is an interview with Dr. Mitra Boolel concerning his early 1996 Viagra study. mediconsult.com;
----------------------------------------------------
I believe BigK that this interview contains alot of hot air blue smoke and mirrors.Let us analyze it CAREFULLY:

Quote; Interviewer asks.". Will sildenafil remove for the need for injected stimulants?

Boolel says "The vast majority of men with erectile dysfunction would prefer an oral therapy to an injection therapy"
HE DOES NOT ANSWER THE QUESTION

NEXT
QUESTION;3. Why was the drug tested on men with erectile dysfunction of no known organic cause?

When we try to establish a cause for erectile dysfunction, we are looking at three big groups. There are men with primarily psychogenic causes, there are men with clear organic causes, and there are men with mixed psychogenic and organic causes.
" In fact it's often difficult to establish a clear cause-and-effect relationship; one can say that a man has diabetes and has impotence, but it's quite a different thing to establish that diabetes is the cause of that impotence.".

THIS IS BALDERDASH; If a patient has diabetes for 10-15 years, with retinal disease and numbness in his legs and coronary artery disease, you are darn well sure that his impotence came from Diabetes and is not Psychogenic.
It is possible that with the above type of thinking, he took the very mild, normal diabetics and gave them the pill.In fact he says so in his nest statement:
" In the study described in this paper, which was one of the first studies we carried out with patients, we picked a population of men who were more likely to respond -- who had no severe organic disease -- in order to maximize the potential for the drug to demonstrate an effect. ".

FINALLY, the whole interview concludes with more ' PSYCHO-BABBLE " < gg > :

QUESTION " 4. What are the roots of erectile dysfunction without organic cause, and can that kind of impotence also be treated with this drug?

We believe that many cases of impotence are psychogenic or have a strong psychogenic component. The roots of such impotence are partly psychological, and anxiety is usually one of them. It's generally true for all compounds used to treat erectile dysfunction that they are more efficient in treating psychogenic impotence than organic impotence, and do so at smaller doses. That is certainly true for injection therapy, for example. We have observed also, with sildenafil, that impotence with organic causes tend to require higher doses.

BigKNY3, I don't think you should hold your breath for Viagra to help truly, severely, impotent men. Certainly not those using the needle.At best it will help those that have psychogenic problems. My opinion.
( based on lengthy analysis of all the available data ).

TA