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Biotech / Medical : Agouron Pharmaceuticals (AGPH) -- Ignore unavailable to you. Want to Upgrade?


To: BriBear who wrote (3480)12/30/1997 8:15:00 PM
From: JOHN W.  Read Replies (2) | Respond to of 6136
 
BriBear, good. Viracept has shown better results with Sustiva than Crixivan. I really don't think that will have a large effect on Viracept sales, but just makes David look stupid.

Come on David, do the Homework? Are you waiting for Friday to take profits?



To: BriBear who wrote (3480)12/30/1997 8:55:00 PM
From: Miljenko Zuanic  Read Replies (1) | Respond to of 6136
 
BB:

You are bit confused by names.

Nucleotide: DNA/RNA base (T, I, A, G, U, C,..) or their analogue + sugar (ribose) + phosphate ester.
Nucleoside: DNA/RNA base + sugar

Difference in one letter is for phosphorylated compounds. Also, any RT drug have to be phosphorylated (active metabolite in body) before they can do any inhibitory effects.

Cidofovir (PMEA) and PMPA are phosphonylmethoxy base derivative and they do not have regular sugar component, or both drug are phosphorylated acyclic nucleotide. So this drug is already active inhibitor, compared to other RT drug.

mz



To: BriBear who wrote (3480)12/31/1997 12:45:00 PM
From: Oliver & Co  Read Replies (1) | Respond to of 6136
 
"Johns Hopkins AIDS Program for Medicaid Patients Efficacious and
Cost-Effective"
Reuters Health Information Services (12/30/97)
ÿÿÿÿ An article in the December 25th issue of Disease Management
News indicates that a new AIDS program for Medicaid patients has
both saved money and increased patient survival. The article
noted that while Medicaid pays nearly $23,000 per patient for
AIDS patients nationwide each year, the average cost of treatment
with the Moore Options AIDS program at Johns Hopkins Hospital in
Maryland is only about $10,000 per patient per year. According to
Dr. John Bartlett, head of the infectious disease division at the
university, the AIDS program helped increase the survival rate of
AIDS patients from inner-city Baltimore, so that patients in that
system had the same likelihood of survival, regardless of
earnings, gender, race, or risk level.
======================================================================

I wonder what combos they are giving patients, to be able to have such low cost.