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To: makin_dough99 who wrote (142)	1/13/1998 2:39:00 PM
From: Graham Marshman	Read Replies (1) \| Respond to of 4028

Good news on telomerase from Geron: Graham +Geron Telomerase Study Shows Extended Human Cell Life Span Geron - Telomerase Study -2: Confirms Earlier Rumors MENLO PARK, Calif. (Dow Jones)--Geron Corp. (GERN) said it extended the life-span of normal human cells using the enzyme telomerase in a study at the University of Texas Southwestern Medical Center. Geron confirmed earlier speculation about the favorable results that sent the company's shares up almost 25%. As reported earlier, an embargoed media advisory offering some details of the study was circulated by PR Newswire and was inadvertently published in its entirety by Dow Jones News/Retrieval, a database service, late Monday afternoon. In a press release Tuesday, Geron said its study showed that the introduction of an active telomerase gene into normal mortal cells resulted in the lengthening of telomeres and a marked increase in the life-span of the cells, making the cells potentially immortal. Telomerase is an "immortalizing" enzyme that imparts replicative immortality when expressed in reproductive and cancer cells. Cells that do not express the enzyme are mortal. Geron, a biopharmaceutical company, is exploring applications of the telomerase gene to extend the life-span of many different types of human cells, including skin cells, blood vessel endothelial cells, retinal cells and immune cells.