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Biotech / Medical : momo-T/FIF -- Ignore unavailable to you. Want to Upgrade?


To: Miljenko Zuanic who wrote (11528)2/8/2018 2:32:36 PM
From: Miljenko Zuanic  Respond to of 12215
 
MDGL CC:

Very confusing and/or not-helping CC, rise more qs than answer them.
Two main concern in regards the MGL-3196 is;
1. Optimal dosing (how to predict when you have selective and specific liver targeting agent), and
2. Magnitude of the effects on lipids and triglycerides, when you do not adjust for placebo (positive drift)???

In all, maybe VK2809 is better agent than 3196, at least for HeFH related conditions (in P1b/2a show better results on factor/marker measurements, more predictable dosing...max 20 mg, titration from 10 mg)???