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Biotech / Medical : Biomatrix (BXM) Looking Great -- Ignore unavailable to you. Want to Upgrade?

To: James B. Barnes who wrote (324)	1/13/1998 12:05:00 AM
From: John McCarthy	Respond to of 569

Hi James, As you know, the bottom line is, the right procedures were followed for your mother. And its great that her cartilage is about the same. With regard to your questions, the other product is HYALGAN which is mfg. by Fidia Pharm and marketed by Sanofi/OrthoLogic. Think you could get it as early as June of last year. Here's a read: slackinc.com\fluid.htm Regards, John

To: James B. Barnes who wrote (324)	1/13/1998 12:08:00 AM
From: Eduardo Canto	Read Replies (3) \| Respond to of 569

James, The product that was approved prior to Synvisc is called Hyalgan and it requires 5 injections. Hard to say without more info, but it seems like your mother is on an ACE inhibitor such as captopril, lisinopril, etc for her hypertension. She was probably given a nonsteroidal anti-inflamatory for her pain. In terms of Synvisc being not indicated for a patient that has their pain controlled by any medicine that is not otherwise threatening to the patient's health, the statement is incorrect. The indication as it appears on the box reads: "Synvisc is indicated for the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy (in other words, no therapy) and simple analgesics, e.g. acetaminophen. (that's Tylenol)" That was the one major victory that Biox brought to the field of hyaluronic acid for OA of the knee. Best, E.C.