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Biotech / Medical : NNVC - NanoViricides, Inc. -- Ignore unavailable to you. Want to Upgrade?


To: andy71 who wrote (10978)8/23/2018 12:59:08 PM
From: Magnus1  Read Replies (1) | Respond to of 12871
 
Yo andy71, it was like we were having the same thought.

Rhut-Roh...I heard that almost exact narrative before...now where was that...and who said it... Rhut-Roh it will come to me in a minute.



To: andy71 who wrote (10978)8/23/2018 6:28:30 PM
From: HardToFind  Read Replies (1) | Respond to of 12871
 
BoredMember and I are different posters, so we are allowed to have different opinions.

I do not presume that they never intended to do tox. I think they intended to do tox, but many things got in the way, only one of which was that the FDA wanted 2.5 kg to do it in large animals.

Some other problems were:
  1. They didn't have good control of their CMC processes.
  2. They didn't test with enough different types of flu viruses.
  3. They were having a very difficult time scaling up to anticipated levels.
Once a delay was unavoidable:
  1. They changed the micelle backbone so that it could be absorbed through the stomach.
  2. They changed the ligands to be more potent...to mitigate the scale-up issues.
The FDA was an easy scapegoat to hide their inability to execute.

Planning and anticipation haven't been great, except for the whole NNVC vs. TheraCour thing. Diwan was largely able to push most of the financial pain onto the NNVC shareholders, as opposed to TheraCour. Dilution will have a minimal impact on TheraCour.

To be clear, I think Seymour was asked/told to leave because Diwan lost patience with him. Boniuk lost his patience with Diwan and left because he wasn't being paid $350K a year to put up with it. Instead, Boniuk was paying millions to put up with it.