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Biotech / Medical : Zonagen (zona) - good buy? -- Ignore unavailable to you. Want to Upgrade?


To: Dr. Voodoo who wrote (1740)1/15/1998 7:12:00 PM
From: poodle  Respond to of 7041
 
Points were:
Looked like someone searched for "secret substance" in Vasomax that increase speed of absorbtion and allow to accumulate effective blood concentration.
I do not think that speed of phentolamine absorbtion is the most important information at this point (It could be important for patent battles and so on ). Does phentolamine at safe concentration help at all seems to be much more important. I did not find in the literature any recomendation to inject phentolamine alone, however recomendations for mixtures injectons (with papaverin, for example) do exist. At this point I do not see any evidence that even direct injections of phentolamine will help. So I have no independent information to compare with Vasomax trial results.
Information that Asensio published:
"In 1988, a study of 15 impotent patients found that 13 achieved a full erection with the drug combination of papaverine and phentolamine but only one achieved a full erection with
phentolamine alone. "

asensio.com
Description of Vsomax.

I believe that the paper he mentioned.

Message 3175381

Somewhere else he also mentioned that this work was performed in West Germany, so I think that's it.

I have full text now.
0.5 mg /ml phentolamine solution
1 ml injection

So final amount was 0.5 mg.
Compare with 40-60 mg used in Vasomax trial. It's oral pill so.... By another words, you have to be professional pharmacologist to make any conclusion...

Why should I go too deep in this subject? I would rather learn contraception, it could be much more usefull at this point. Any idea to short contraceptive provider?