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Biotech / Medical : momo-T/FIF -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (11668)9/18/2018 11:55:27 AM
From: Miljenko Zuanic  Read Replies (2) | Respond to of 12215
 
RE: VKTX
Just finished CC (I like to sleep longer this days, :-))

While I am gratified that VK2809 did have positive primary and secondary, and most importantly NO safety (so far NO) issue at 10 mg/day dose (I care less for QOD regime, maybe they can introduce 5 mg/day dose???),....there is several points that make me MAD! IS THERE ANY BIO-COMPANY THAT CAN REPORT STRAIT FORWARD RESULTS???

First, when company switch the importance of the end-points (those are pHeHF subjects , not NASH) and exclude arm as trial progress without reporting,...I PISS ON THEM!

Second, when company report numbers for secondary and no numbers for primary (15-40%LDLc reduction relative to placebo is only range, and not mean/median),...I PISS ON THEM!

Third, when company is talking too-much about option to scale down dose,...THAN I ASK: "WHAT IS FUCKING WRONG WITH CURRENT DOSE/REGIMEN???"

Looking forward to full data presentation.

I was slow this morning, so full position on VKTX is still in place.